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Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction

Altered cellular metabolism is an important characteristic and driver of cancer. Surprisingly, however, we find here that aggregating individual gene expression using canonical metabolic pathways fails to enhance the classification of noncancerous vs. cancerous tissues and the prediction of cancer p...

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Bibliografiska uppgifter
I publikationen:PLoS Comput Biol
Huvudupphovsmän: Auslander, Noam, Wagner, Allon, Oberhardt, Matthew, Ruppin, Eytan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038951/
https://ncbi.nlm.nih.gov/pubmed/27673682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005125
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