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Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction

Altered cellular metabolism is an important characteristic and driver of cancer. Surprisingly, however, we find here that aggregating individual gene expression using canonical metabolic pathways fails to enhance the classification of noncancerous vs. cancerous tissues and the prediction of cancer p...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Auslander, Noam, Wagner, Allon, Oberhardt, Matthew, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038951/
https://ncbi.nlm.nih.gov/pubmed/27673682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005125
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