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Mutational Consequences of Ciprofloxacin in Escherichia coli

We examined the mutagenic specificity of the widely used antibiotic ciprofloxacin (CPR), which displays weak to moderate mutagenic activity in several bacteria and generates short in-frame deletions in rpoB in Staphylococcus aureus. To determine the spectrum of mutations in a system where any gene k...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Song, Lisa Yun, Goff, Marisa, Davidian, Christina, Mao, Zhiyuan, London, Marisa, Lam, Karen, Yung, Madeline, Miller, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038312/
https://ncbi.nlm.nih.gov/pubmed/27480851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01415-16
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