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Mutational Consequences of Ciprofloxacin in Escherichia coli

We examined the mutagenic specificity of the widely used antibiotic ciprofloxacin (CPR), which displays weak to moderate mutagenic activity in several bacteria and generates short in-frame deletions in rpoB in Staphylococcus aureus. To determine the spectrum of mutations in a system where any gene k...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Song, Lisa Yun, Goff, Marisa, Davidian, Christina, Mao, Zhiyuan, London, Marisa, Lam, Karen, Yung, Madeline, Miller, Jeffrey H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038312/
https://ncbi.nlm.nih.gov/pubmed/27480851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01415-16
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