Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp.

Genome sequencing projects in the last decade revealed numerous cryptic biosynthetic pathways for unknown secondary metabolites in microbes, revitalizing drug discovery from microbial metabolites by approaches called genome mining. In this work, we developed a heterologous expression and functional...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Xu, Min, Wang, Yemin, Zhao, Zhilong, Gao, Guixi, Huang, Sheng-Xiong, Kang, Qianjin, He, Xinyi, Lin, Shuangjun, Pang, Xiuhua, Deng, Zixin, Tao, Meifeng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038051/
https://ncbi.nlm.nih.gov/pubmed/27451447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01383-16
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker