OX133, a monoclonal antibody recognizing protein-bound N-ethylmaleimide for the identification of reduced disulfide bonds in proteins

In vivo, enzymatic reduction of some protein disulfide bonds, allosteric disulfide bonds, provides an important level of structural and functional regulation. The free cysteine residues generated can be labeled by maleimide reagents, including biotin derivatives, allowing the reduced protein to be d...

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Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Holbrook, Lisa-Marie, Kwong, Lai-Shan, Metcalfe, Clive L., Fenouillet, Emmanuel, Jones, Ian M., Barclay, A. Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037987/
https://ncbi.nlm.nih.gov/pubmed/26986548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1152443
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