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Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor

Certain disulfide bonds present in leucocyte membrane proteins are labile and can be reduced in inflammation. This can cause structural changes that result in downstream functional effects, for example, in integrin activation. Recent studies have shown that a wide range of membrane proteins have lab...

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Bibliografski detalji
Glavni autori: Metcalfe, Clive, Cresswell, Peter, Barclay, A. Neil
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352089/
https://ncbi.nlm.nih.gov/pubmed/22645657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.110036
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