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OX133, a monoclonal antibody recognizing protein-bound N-ethylmaleimide for the identification of reduced disulfide bonds in proteins

In vivo, enzymatic reduction of some protein disulfide bonds, allosteric disulfide bonds, provides an important level of structural and functional regulation. The free cysteine residues generated can be labeled by maleimide reagents, including biotin derivatives, allowing the reduced protein to be d...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Holbrook, Lisa-Marie, Kwong, Lai-Shan, Metcalfe, Clive L., Fenouillet, Emmanuel, Jones, Ian M., Barclay, A. Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037987/
https://ncbi.nlm.nih.gov/pubmed/26986548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1152443
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