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The transcription factor AP4 mediates resolution of chronic viral infection through amplification of germinal center B cell responses

B cells diversify and affinity-mature their antigen receptor repertoire in germinal centers (GC). GC B cells receive help signals during transient interaction with T cells, yet it remains unknown how these transient T-B interactions in the light zone sustain the subsequent proliferative program of s...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Chou, Chun, Verbaro, Daniel J., Tonc, Elena, Holmgren, Melanie, Cella, Marina, Colonna, Marco, Bhattacharya, Deepta, Egawa, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037962/
https://ncbi.nlm.nih.gov/pubmed/27566940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.07.023
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