c-Myc-induced transcription factor AP4 is required for CD8(+) T cell-mediated host protection

Although c-Myc is essential to establish a metabolically active and proliferative state in T cells after priming, its expression is transient. It remains unknown how T cell activation is maintained after c-Myc down-regulation. Here, we identify AP4 as the transcription factor that is induced by c-My...

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Bibliographische Detailangaben
Hauptverfasser: Chou, Chun, Pinto, Amelia K., Curtis, Jonathan D., Persaud, Stephen P., Cella, Marina, Lin, Chih-Chung, Edelson, Brian T., Allen, Paul M., Colonna, Marco, Pearce, Erika L., Diamond, Michael S., Egawa, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139462/
https://ncbi.nlm.nih.gov/pubmed/25029552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2943
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