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c-Myc-induced transcription factor AP4 is required for CD8(+) T cell-mediated host protection
Although c-Myc is essential to establish a metabolically active and proliferative state in T cells after priming, its expression is transient. It remains unknown how T cell activation is maintained after c-Myc down-regulation. Here, we identify AP4 as the transcription factor that is induced by c-My...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139462/ https://ncbi.nlm.nih.gov/pubmed/25029552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2943 |
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