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Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis

Fas and Fas Ligand (FasL) are two molecules involved in the regulation of cell death. Their interaction leads to apoptosis of thymocytes that fail to rearrange correctly their T cell receptor (TCR) genes and of those that recognize self-antigens, a process called negative selection; moreover, Fas–Fa...

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Foilsithe in:Front Immunol
Main Authors: Volpe, Elisabetta, Sambucci, Manolo, Battistini, Luca, Borsellino, Giovanna
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037862/
https://ncbi.nlm.nih.gov/pubmed/27729910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00382
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