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Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis
Fas and Fas Ligand (FasL) are two molecules involved in the regulation of cell death. Their interaction leads to apoptosis of thymocytes that fail to rearrange correctly their T cell receptor (TCR) genes and of those that recognize self-antigens, a process called negative selection; moreover, Fas–Fa...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037862/ https://ncbi.nlm.nih.gov/pubmed/27729910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00382 |
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