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Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis

Fas and Fas Ligand (FasL) are two molecules involved in the regulation of cell death. Their interaction leads to apoptosis of thymocytes that fail to rearrange correctly their T cell receptor (TCR) genes and of those that recognize self-antigens, a process called negative selection; moreover, Fas–Fa...

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Publicat a:Front Immunol
Autors principals: Volpe, Elisabetta, Sambucci, Manolo, Battistini, Luca, Borsellino, Giovanna
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037862/
https://ncbi.nlm.nih.gov/pubmed/27729910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00382
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