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Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis

Fas and Fas Ligand (FasL) are two molecules involved in the regulation of cell death. Their interaction leads to apoptosis of thymocytes that fail to rearrange correctly their T cell receptor (TCR) genes and of those that recognize self-antigens, a process called negative selection; moreover, Fas–Fa...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Volpe, Elisabetta, Sambucci, Manolo, Battistini, Luca, Borsellino, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037862/
https://ncbi.nlm.nih.gov/pubmed/27729910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00382
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