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Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis

Fas and Fas Ligand (FasL) are two molecules involved in the regulation of cell death. Their interaction leads to apoptosis of thymocytes that fail to rearrange correctly their T cell receptor (TCR) genes and of those that recognize self-antigens, a process called negative selection; moreover, Fas–Fa...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Volpe, Elisabetta, Sambucci, Manolo, Battistini, Luca, Borsellino, Giovanna
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037862/
https://ncbi.nlm.nih.gov/pubmed/27729910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00382
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