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Kinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-Cells

Pancreatic β-cell failure and death is considered to be one of the main factors responsible for type 2 diabetes. It is caused by, in addition to hyperglycemia, chronic exposure to increased concentrations of fatty acids, mainly saturated fatty acids. Molecular mechanisms of apoptosis induction by sa...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Šrámek, Jan, Němcová-Fürstová, Vlasta, Kovář, Jan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037680/
https://ncbi.nlm.nih.gov/pubmed/27626409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17091400
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