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Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells

BACKGROUND: In the context of tumor immunology, tumor cells have been shown to overexpress CD47, an anti-phagocytic signal directed to macrophages to escape from phagocytosis by interacting with Signal Regulatory Protein α SIRPα. In the present work, we designed Polypurine reverse Hoogsteen hairpins...

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Bibliografski detalji
Izdano u:BMC Immunol
Glavni autori: Bener, Gizem, J. Félix, Alex, Sánchez de Diego, Cristina, Pascual Fabregat, Isabel, Ciudad, Carlos J., Noé, Véronique
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037635/
https://ncbi.nlm.nih.gov/pubmed/27671753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0170-z
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