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Repair of Single-Point Mutations by Polypurine Reverse Hoogsteen Hairpins
Polypurine reverse Hoogsteen hairpins (PPRHs) are formed by two intramolecularly bound antiparallel homopurine domains linked by a five-thymidine loop. One of the homopurine strands binds with antiparallel orientation by Watson–Crick bonds to the polypyrimidine target sequence, forming a triplex. We...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Mary Ann Liebert, Inc.
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4208591/ https://ncbi.nlm.nih.gov/pubmed/25222154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.049 |
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