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Repair of Single-Point Mutations by Polypurine Reverse Hoogsteen Hairpins

Polypurine reverse Hoogsteen hairpins (PPRHs) are formed by two intramolecularly bound antiparallel homopurine domains linked by a five-thymidine loop. One of the homopurine strands binds with antiparallel orientation by Watson–Crick bonds to the polypyrimidine target sequence, forming a triplex. We...

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Detalhes bibliográficos
Main Authors: Solé, Anna, Villalobos, Xenia, Ciudad, Carlos J., Noé, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208591/
https://ncbi.nlm.nih.gov/pubmed/25222154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.049
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