Suppressed expression of miR-378 targeting gzmb in NK cells is required to control dengue virus infection

Dengue virus (DENV) remains a major public health threat because no vaccine or drugs are available for the prevention and treatment of DENV infection, and the immunopathogenesis mechanisms of DENV infection are not fully understood. Cytotoxic molecules, such as granzyme B (GrzB), may be necessary to...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Mol Immunol
Auteurs principaux: Liu, Shuyan, Chen, Lingming, Zeng, Ying, Si, Lulu, Guo, Xiaolan, Zhou, Junmei, Fang, Danyun, Zeng, Gucheng, Jiang, Lifang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037283/
https://ncbi.nlm.nih.gov/pubmed/26166761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.52
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