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Suppressed expression of miR-378 targeting gzmb in NK cells is required to control dengue virus infection

Dengue virus (DENV) remains a major public health threat because no vaccine or drugs are available for the prevention and treatment of DENV infection, and the immunopathogenesis mechanisms of DENV infection are not fully understood. Cytotoxic molecules, such as granzyme B (GrzB), may be necessary to...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Liu, Shuyan, Chen, Lingming, Zeng, Ying, Si, Lulu, Guo, Xiaolan, Zhou, Junmei, Fang, Danyun, Zeng, Gucheng, Jiang, Lifang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037283/
https://ncbi.nlm.nih.gov/pubmed/26166761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.52
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