Replacement of pr gene with Japanese encephalitis virus pr using reverse genetics reduces antibody-dependent enhancement of dengue virus 2 infection

Severe dengue is more likely found during secondary heterologous dengue virus (DENV) infection or primary infection of infants born to dengue-immune mothers and led to the hypothesis of antibody-dependent enhancement (ADE). It has been reported that pre-membrane (prM)-reactive antibodies do not effi...

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Detalhes bibliográficos
Publicado no:Appl Microbiol Biotechnol
Main Authors: Wang, Ying, Si, Lulu, Luo, Yayan, Guo, Xiaolan, Zhou, Junmei, Fang, Danyun, Yan, Huijun, Zeng, Gucheng, Jiang, Lifang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Applied Genetics and Molecular Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628084/
https://ncbi.nlm.nih.gov/pubmed/26219500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-015-6819-3
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