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The Notch intracellular domain has an RBPj-independent role during mouse hair follicular development
Ligand-dependent activation, γ-secretase-processed cleavage, and RBPj-mediated downstream transcriptional activities of Notch receptors constitute the “canonical” Notch signaling pathway, which is essential for skin organogenesis. However, in Msx2-Cre mice, keratinocyte-specific deletion of the Rbpj...
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| Publicado no: | J Invest Dermatol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036938/ https://ncbi.nlm.nih.gov/pubmed/26940862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.02.018 |
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