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The Notch intracellular domain has an RBPj-independent role during mouse hair follicular development

Ligand-dependent activation, γ-secretase-processed cleavage, and RBPj-mediated downstream transcriptional activities of Notch receptors constitute the “canonical” Notch signaling pathway, which is essential for skin organogenesis. However, in Msx2-Cre mice, keratinocyte-specific deletion of the Rbpj...

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Bibliografski detalji
Izdano u:J Invest Dermatol
Glavni autori: Turkoz, Mustafa, Townsend, R. Reid, Kopan, Raphael
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036938/
https://ncbi.nlm.nih.gov/pubmed/26940862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.02.018
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