Identification of Genome-Wide Mutations in Ciprofloxacin-Resistant F. tularensis LVS Using Whole Genome Tiling Arrays and Next Generation Sequencing

Francisella tularensis is classified as a Class A bioterrorism agent by the U.S. government due to its high virulence and the ease with which it can be spread as an aerosol. It is a facultative intracellular pathogen and the causative agent of tularemia. Ciprofloxacin (Cipro) is a broad spectrum ant...

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Pubblicato in:PLoS One
Autori principali: Jaing, Crystal J., McLoughlin, Kevin S., Thissen, James B., Zemla, Adam, Gardner, Shea N., Vergez, Lisa M., Bourguet, Feliza, Mabery, Shalini, Fofanov, Viacheslav Y., Koshinsky, Heather, Jackson, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036845/
https://ncbi.nlm.nih.gov/pubmed/27668749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163458
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