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Pressure acceleration of proteolysis: A general mechanism
Remarkable acceleration of enzymatic proteolysis by pressure at kbar range is reported with ubiquitin as substrate and α-chymotrypsin as enzyme. The acceleration is interpreted in terms of the shift of conformational equilibrium in ubiquitin from the non-degradable folded conformer to the enzyme-deg...
Gardado en:
| Publicado en: | Biophysics (Nagoya-shi) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society of Japan (BSJ)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036607/ https://ncbi.nlm.nih.gov/pubmed/27857573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysics.4.29 |
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