Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study

BACKGROUND: A fixed-dose combination (FDC) of amlodipine and losartan has been used to reduce blood pressure in patients whose hypertension is not sufficiently controlled with either drug alone. The aim of this study was to evaluate the pharmacokinetic (PK) characteristics and tolerability of an FDC...

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Detalles Bibliográficos
Publicado en:Drug Des Devel Ther
Main Authors: Choi, YoonJung, Lee, SeungHwan, Cho, Sang-Min, Kang, Won-Ho, Nam, Kyu-Yeol, Jang, In-Jin, Yu, Kyung-Sang
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2016
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036556/
https://ncbi.nlm.nih.gov/pubmed/27703330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S113891
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