Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study

BACKGROUND: A fixed-dose combination (FDC) of amlodipine and losartan has been used to reduce blood pressure in patients whose hypertension is not sufficiently controlled with either drug alone. The aim of this study was to evaluate the pharmacokinetic (PK) characteristics and tolerability of an FDC...

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Publicado en:Drug Des Devel Ther
Autores principales: Choi, YoonJung, Lee, SeungHwan, Cho, Sang-Min, Kang, Won-Ho, Nam, Kyu-Yeol, Jang, In-Jin, Yu, Kyung-Sang
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2016
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036556/
https://ncbi.nlm.nih.gov/pubmed/27703330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S113891
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