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Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis
The accumulation of lipids is a histologic and biochemical hallmark of obesity-associated nonalcoholic fatty liver disease (NAFLD). A subset of NALFD patients develops progressive liver disease, termed nonalcoholic steatohepatitis, which is characterized by hepatocellular apoptosis and innate immune...
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| Veröffentlicht in: | J Lipid Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036373/ https://ncbi.nlm.nih.gov/pubmed/27049024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R066357 |
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