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Spatiotemporal dynamics of lesion-induced axonal sprouting and its relation to functional architecture of the cerebellum

Neurodegenerative lesions induce sprouting of new collaterals from surviving axons, but the extent to which this form of axonal remodelling alters brain functional structure remains unclear. To understand how collateral sprouting proceeds in the adult brain, we imaged post-lesion sprouting of cerebe...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Dhar, Matasha, Brenner, Joshua M., Sakimura, Kenji, Kano, Masanobu, Nishiyama, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036008/
https://ncbi.nlm.nih.gov/pubmed/27651000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12938
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