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Postsynaptic P/Q-type Ca(2+) channel in Purkinje cell mediates synaptic competition and elimination in developing cerebellum

Neural circuits are initially redundant but rearranged through activity-dependent synapse elimination during postnatal development. This process is crucial for shaping mature neural circuits and for proper brain function. At birth, Purkinje cells (PCs) in the cerebellum are innervated by multiple cl...

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Detalhes bibliográficos
Main Authors: Hashimoto, Kouichi, Tsujita, Mika, Miyazaki, Taisuke, Kitamura, Kazuo, Yamazaki, Maya, Shin, Hee-Sup, Watanabe, Masahiko, Sakimura, Kenji, Kano, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116426/
https://ncbi.nlm.nih.gov/pubmed/21628556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101488108
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