Functional Equivalence of Retroviral MA Domains in Facilitating Psi RNA Binding Specificity by Gag

Retroviruses specifically package full-length, dimeric genomic RNA (gRNA) even in the presence of a vast excess of cellular RNA. The “psi” (Ψ) element within the 5′-untranslated region (5′UTR) of gRNA is critical for packaging through interaction with the nucleocapsid (NC) domain of Gag. However, in...

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Publicat a:Viruses
Autors principals: Rye-McCurdy, Tiffiny, Olson, Erik D., Liu, Shuohui, Binkley, Christiana, Reyes, Joshua-Paolo, Thompson, Brian R., Flanagan, John M., Parent, Leslie J., Musier-Forsyth, Karin
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035970/
https://ncbi.nlm.nih.gov/pubmed/27657107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8090256
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