Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs: Implications for viral genomic RNA packaging

Despite the vast excess of cellular RNAs, precisely two copies of viral genomic RNA (gRNA) are selectively packaged into new human immunodeficiency type 1 (HIV-1) particles via specific interactions between the HIV-1 Gag and the gRNA psi (ψ) packaging signal. Gag consists of the matrix (MA), capsid,...

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Bibliographic Details
Main Authors: Webb, Joseph A., Jones, Christopher P., Parent, Leslie J., Rouzina, Ioulia, Musier-Forsyth, Karin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708528/
https://ncbi.nlm.nih.gov/pubmed/23798665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.038869.113
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