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Prognostic role of tumor PIK3CA mutation in colorectal cancer: a systematic review and meta-analysis
BACKGROUND: Somatic mutations in the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway play a vital role in carcinogenesis. Approximately 15%–20% of colorectal cancers (CRCs) harbor activating mutations in PIK3CA, making it one of the most frequently mutated genes in CRC. We thus carried ou...
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| Publicado no: | Ann Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035784/ https://ncbi.nlm.nih.gov/pubmed/27436848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdw264 |
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