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Why Is there a Limit to the Changes in Myofilament Ca(2+)-Sensitivity Associated with Myopathy Causing Mutations?

Mutations in striated muscle contractile proteins have been found to be the cause of a number of inherited muscle diseases; in most cases the mechanism proposed for causing the disease is derangement of the thin filament-based Ca(2+)-regulatory system of the muscle. When considering the results of e...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autor principal: Marston, Steven B.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035734/
https://ncbi.nlm.nih.gov/pubmed/27725803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00415
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