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Physiologic Variations in Blood Plasminogen Levels Affect Outcomes after Acute Cerebral Thromboembolism in Mice: A Pathophysiologic Role for Microvascular Thrombosis

BACKGROUND AND OBJECTIVES: Plasminogen appears to affect brain inflammation, cell movement, fibrinolysis, neuronal excitotoxicity and cell death. However, brain tissue and circulating blood plasminogen may have different roles and, there is large individual variation in blood plasminogen levels. The...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Singh, Satish, Houng, Aiilyan K., Wang, Dong, Reed, Guy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035596/
https://ncbi.nlm.nih.gov/pubmed/27319402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13390
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