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Physiologic Variations in Blood Plasminogen Levels Affect Outcomes after Acute Cerebral Thromboembolism in Mice: A Pathophysiologic Role for Microvascular Thrombosis

BACKGROUND AND OBJECTIVES: Plasminogen appears to affect brain inflammation, cell movement, fibrinolysis, neuronal excitotoxicity and cell death. However, brain tissue and circulating blood plasminogen may have different roles and, there is large individual variation in blood plasminogen levels. The...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Singh, Satish, Houng, Aiilyan K., Wang, Dong, Reed, Guy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035596/
https://ncbi.nlm.nih.gov/pubmed/27319402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13390
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