IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression

BACKGROUND: Diffuse gliomas are poorly immunogenic, fatal brain tumors. The basis for insufficient antitumor immunity in diffuse gliomas is unknown. Gain-of-function mutations in isocitrate dehydrogenases (IDH1 and IDH2) promote diffuse glioma formation through epigenetic reprogramming of a number o...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Zhang, Xiaoran, Rao, Aparana, Sette, Paola, Deibert, Christopher, Pomerantz, Alexander, Kim, Wi Jin, Kohanbash, Gary, Chang, Yigang, Park, Yongseok, Engh, Johnathan, Choi, Jaehyuk, Chan, Timothy, Okada, Hideho, Lotze, Michael, Grandi, Paola, Amankulor, Nduka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Basic and Translational Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035522/
https://ncbi.nlm.nih.gov/pubmed/27116977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now061
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller