IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression

BACKGROUND: Diffuse gliomas are poorly immunogenic, fatal brain tumors. The basis for insufficient antitumor immunity in diffuse gliomas is unknown. Gain-of-function mutations in isocitrate dehydrogenases (IDH1 and IDH2) promote diffuse glioma formation through epigenetic reprogramming of a number o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhang, Xiaoran, Rao, Aparana, Sette, Paola, Deibert, Christopher, Pomerantz, Alexander, Kim, Wi Jin, Kohanbash, Gary, Chang, Yigang, Park, Yongseok, Engh, Johnathan, Choi, Jaehyuk, Chan, Timothy, Okada, Hideho, Lotze, Michael, Grandi, Paola, Amankulor, Nduka
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035522/
https://ncbi.nlm.nih.gov/pubmed/27116977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now061
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados