Medroxyprogesterone acetate and levonorgestrel increase genital mucosal permeability and enhance susceptibility to genital herpes simplex virus type 2 infection

Depot-medroxyprogesterone acetate (DMPA) is a hormonal contraceptive especially popular in areas with high prevalence of HIV and other sexually transmitted infections (STI). While observational studies identify DMPA as an important STI risk factor, mechanisms underlying this connection are undefined...

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Publicat a:Mucosal Immunol
Autors principals: Calla, Nirk E Quispe, Miguel, Rodolfo D Vicetti, Boyaka, Prosper N, Hall-Stoodley, Luanne, Kaur, Balveen, Trout, Wayne, Pavelko, Stephen D, Cherpes, Thomas L
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035233/
https://ncbi.nlm.nih.gov/pubmed/27007679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.22
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