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Medroxyprogesterone acetate and levonorgestrel increase genital mucosal permeability and enhance susceptibility to genital herpes simplex virus type 2 infection

Depot-medroxyprogesterone acetate (DMPA) is a hormonal contraceptive especially popular in areas with high prevalence of HIV and other sexually transmitted infections (STI). While observational studies identify DMPA as an important STI risk factor, mechanisms underlying this connection are undefined...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Calla, Nirk E Quispe, Miguel, Rodolfo D Vicetti, Boyaka, Prosper N, Hall-Stoodley, Luanne, Kaur, Balveen, Trout, Wayne, Pavelko, Stephen D, Cherpes, Thomas L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035233/
https://ncbi.nlm.nih.gov/pubmed/27007679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.22
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