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Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy
Diabetes elevates matrix metalloproteinase-9 (MMP-9) in the retina and its capillary cells, and activated MMP-9 damages mitochondria, accelerating retinal capillary cell apoptosis, a phenomenon which precedes the development of retinopathy. Diabetes also favors epigenetic modifications regulating ex...
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| Publicado no: | Lab Invest |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035192/ https://ncbi.nlm.nih.gov/pubmed/27454437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.78 |
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