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Role of Matrix Metalloproteinase-9 in the Development of Diabetic Retinopathy and Its Regulation by H-Ras

PURPOSE. Diabetes activates a small molecular weight G-protein, H-Ras, in the retina and its capillary cells, and H-Ras activation is implicated in the apoptosis of retinal capillary cells. Matrix metalloproteinase (MMP)-9 is regulated by H-Ras, and in diabetes its activation is associated with incr...

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Detalhes bibliográficos
Autor principal: Kowluru, Renu A.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910650/
https://ncbi.nlm.nih.gov/pubmed/20220057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4851
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