Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly

OBJECTIVE: To better understand cross-sectional relationships between CSF and PET measures of tau pathology, we compared regional and global measures of (18)F-T807 (AV-1451) PET to CSF protein levels of total tau (t-tau), phosphorylated tau (p-tau), and β-amyloid 1–42 (Aβ42). METHODS: T-tau, p-tau,...

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Pubblicato in:Neurology
Autori principali: Chhatwal, Jasmeer P., Schultz, Aaron P., Marshall, Gad A., Boot, Brendon, Gomez-Isla, Teresa, Dumurgier, Julien, LaPoint, Molly, Scherzer, Clemens, Roe, Allyson D., Hyman, Bradley T., Sperling, Reisa A., Johnson, Keith A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035159/
https://ncbi.nlm.nih.gov/pubmed/27473132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003050
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