Seipin is required for converting nascent to mature lipid droplets

How proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood. Using Drosophila and human cells, we show here that seipin, an ER protein implicated in LD biology, mediates a discrete step in LD formation—the conversion of small, nascent LDs to larger, mature LDs. Seipin f...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Wang, Huajin, Becuwe, Michel, Housden, Benjamin E, Chitraju, Chandramohan, Porras, Ashley J, Graham, Morven M, Liu, Xinran N, Thiam, Abdou Rachid, Savage, David B, Agarwal, Anil K, Garg, Abhimanyu, Olarte, Maria-Jesus, Lin, Qingqing, Fröhlich, Florian, Hannibal-Bach, Hans Kristian, Upadhyayula, Srigokul, Perrimon, Norbert, Kirchhausen, Tomas, Ejsing, Christer S, Walther, Tobias C, Farese, Robert V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2016
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035145/
https://ncbi.nlm.nih.gov/pubmed/27564575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16582
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