Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models

Current treatments available for African sleeping sickness or human African trypanosomiasis (HAT) are limited, with poor efficacy and unacceptable safety profiles. Here, we report a new approach to address treatment of this disease based on the use of compounds that bind to parasite surface glycans...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:PLoS Pathog
Main Authors: Castillo-Acosta, Víctor M., Ruiz-Pérez, Luis M., Etxebarria, Juan, Reichardt, Niels C., Navarro, Miguel, Igarashi, Yasuhiro, Liekens, Sandra, Balzarini, Jan, González-Pacanowska, Dolores
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035034/
https://ncbi.nlm.nih.gov/pubmed/27662652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005851
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla