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Specificity of the connexin W3/4 locus for functional gap junction formation

The N-terminal (NT) domain of the connexins forms an essential transjunctional voltage (V(j)) sensor and pore-forming domain that when truncated, tagged, or mutated often leads to formation of a nonfunctional channel. The NT domain is relatively conserved among the connexins though the α- and δ-grou...

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Foilsithe in:Channels (Austin)
Main Authors: Xu, Qin, Lin, Xianming, Matiukas, Arvydas, Zhang, Xian, Veenstra, Richard D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034775/
https://ncbi.nlm.nih.gov/pubmed/27304225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2016.1200775
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