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Positive and Negative Cross-Talk between Lysophosphatidic Acid Receptor 1, Free Fatty Acid Receptor 4, and Epidermal Growth Factor Receptor in Human Prostate Cancer Cells
Lysophosphatidic acid (LPA) is a lipid mediator that mediates cellular effects via G protein–coupled receptors (GPCRs). Epidermal growth factor (EGF) is a peptide that acts via a receptor tyrosine kinase. LPA and EGF both induce proliferation of prostate cancer cells and can transactivate each other...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034703/ https://ncbi.nlm.nih.gov/pubmed/27474750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.233379 |
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