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Eicosopentaneoic Acid and Other Free Fatty Acid Receptor Agonists Inhibit Lysophosphatidic Acid- and Epidermal Growth Factor-Induced Proliferation of Human Breast Cancer Cells

Many key actions of ω-3 (n-3) fatty acids have recently been shown to be mediated by two G protein-coupled receptors (GPCRs) in the free fatty acid receptor (FFAR) family, FFA1 (GPR40) and FFA4 (GPR120). n-3 Fatty acids inhibit proliferation of human breast cancer cells in culture and in animals. In...

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Pubblicato in:J Clin Med
Autori principali: Hopkins, Mandi M., Zhang, Zhihong, Liu, Ze, Meier, Kathryn E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773772/
https://ncbi.nlm.nih.gov/pubmed/26821052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5020016
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