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TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway
OBJECTIVE: Obesity and type 2 diabetes (T2D) lead to various life-threatening diseases such as coronary heart disease, stroke, osteoarthritis, asthma, and neurodegeneration. Therefore, extensive research is ongoing to identify novel pathways that can be targeted in obesity/T2D. Deletion of the inosi...
Tallennettuna:
Julkaisussa: | Mol Metab |
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Päätekijät: | , , , , , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Elsevier
2016
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034689/ https://ncbi.nlm.nih.gov/pubmed/27689003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.08.008 |
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