A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens

BACKGROUND: The polymorphic nature of many malaria vaccine candidates presents major challenges to achieving highly efficacious vaccines. Presently, there is very little knowledge on the prevalence and patterns of functional immune responses to polymorphic vaccine candidates in populations to guide...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Drew, Damien R., Wilson, Danny W., Elliott, Salenna R., Cross, Nadia, Terheggen, Ulrich, Hodder, Anthony N., Siba, Peter M., Chelimo, Kiprotich, Dent, Arlene E., Kazura, James W., Mueller, Ivo, Beeson, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034621/
https://ncbi.nlm.nih.gov/pubmed/27658419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-016-0691-6
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