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Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children
BACKGROUND: Antibodies targeting Plasmodium falciparum sporozoites play a key role in human immunity to malaria. However, antibody mechanisms that neutralize sporozoites are poorly understood. This has been a major constraint in developing highly efficacious vaccines, as we lack strong correlates of...
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| Опубликовано в: : | BMC Med |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5925837/ https://ncbi.nlm.nih.gov/pubmed/29706136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1054-2 |
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