Fibroblast activation protein (FAP) as a novel metabolic target

OBJECTIVE: Fibroblast activation protein (FAP) is a serine protease belonging to a S9B prolyl oligopeptidase subfamily. This enzyme has been implicated in cancer development and recently reported to regulate degradation of FGF21, a potent metabolic hormone. Using a known FAP inhibitor, talabostat (T...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Sánchez-Garrido, Miguel Angel, Habegger, Kirk M., Clemmensen, Christoffer, Holleman, Cassie, Müller, Timo D., Perez-Tilve, Diego, Li, Pengyun, Agrawal, Archita S., Finan, Brian, Drucker, Daniel J., Tschöp, Matthias H., DiMarchi, Richard D., Kharitonenkov, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034526/
https://ncbi.nlm.nih.gov/pubmed/27689014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.07.003
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