Mitigation of indomethacin-induced gastrointestinal damages in fat-1 transgenic mice via gate-keeper action of ω-3-polyunsaturated fatty acids

Non-steroidal anti-inflammatory drugs (NSAIDs) damage the gastrointestinal (GI) epithelial cell membranes by inducing several signals through lipid raft organization after membrane incorporation, whereas ω-3 polyunsaturated fatty acids (PUFAs) relieve inflammation, reduce oxidative stress, and provi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Han, Young-Min, Park, Jong-Min, Kang, Jing X., Cha, Ji-Young, Lee, Ho-Jae, Jeong, Migeyong, Go, Eun-Jin, Hahm, Ki Baik
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034283/
https://ncbi.nlm.nih.gov/pubmed/27658533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33992
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